Are you looking for best systemic enzymes, we’ve consulted top experts who has in-and-out knowledge about the systemic enzymes. We choose the top most quality product, which comes with amazing features you’ve never heard before. We have filter more than 100+ of product to give you top 10 list of best systemic enzymes.

This list is undoubtedly the best systemic enzymes available in the market today. However, if you don’t want to spend more time on filtering and finding which one is good systemic enzymes, then you should absolutely go for our Top list of the winner. which comes with all the basic features one could expect in a systemic enzymes.


Best systemic enzymes – The Winners!


But these three has some more competitions too, Check out below List of Top 10 best systemic enzymes.

If you are ready to choose a new systemic enzymes, check out our recommendations for the best systemic enzymes. But if you’d like to learn more about the various types of systemic enzymes available and how to choose the right one for you, read on.


List of Top 10 Best systemic enzymes In Detailed


Bestseller No. 1
Garden of Life Joint Supplement for Men and Women - Wobenzym N Systemic Enzymes, Clinically Studied Formula for Healthy Joints, Mobility, Flexibility, Post-Exercise Recovery, Gluten Free, 200 Tablets
  • THE CLINICALLY STUDIED FORMULA: First introduced in Germany over 40 years ago, the Wobenzym N formula includes pancreatin protease, papain, bromelain, trypsin, chymotrypsin, rutoside trihydrate to help maintain healthy joints, mobility and flexibility
  • A TRADITION OF SUCCESS: Wobenzym N is a global leader in joint health and is the only systemic enzyme formula backed by decades of clinical research and customer satisfaction; Systemic enzymes work throughout the entire body to support overall joint health
  • HELPS IMPROVE JOINT COMFORT AND RANGE OF MOTION: Get going with Wobenzym N, the authentic systemic enzyme formula trusted by millions worldwide to provide clinically demonstrated support for joint & tendon health; For speedy recovery following exertion
  • GLUTEN FREE AND DAIRY FREE SYSTEMIC ENZYME FORMULA: A synergistic combination of plant-based enzymes, pancreatic enzymes & antioxidants—with Carica papaya and Sophora japonica; Temporary relief from aches, pains & muscle soreness due to everyday activity
  • FUEL YOUR HEALTH: Enzymes are essential biological catalysts involved in almost every single process in our bodies; Our powerful yet delicate enzymes are protected by a vegetable-based enteric coating for optimal absorption and utilization
Bestseller No. 2
Serrapeptase Enzymes | Up to 2 Month Supply | Vegan Serrapeptase High Potency Sinus Relief Pills for Allergy Support, Tissue Health and Cellular Health | Plant Based, Vegan Capsule | Enteric Coated
  • Serrapeptase Systemic Enzymes: This proprietary blend of enteric-coated Serrapeptase (also known as Serratiopeptidase) and a Protease blend is combined with enzyme enhancing vitamins and minerals to support your overall health. Encapsulated in pine-based vegan capsules, you can easily incorporate these into your routine.
  • Multiple Benefits: Serrapeptase may help to support the body's circulatory system, healthy tissue homeostasis, and the body’s natural inflammation process. This powerful enzyme blend may support cellular, tissue, and systemic health, while promoting healthy immune activity and aiding your body in maintaining normal microbial balance.
  • Advanced Enzyme Complex: 120,000 SPU Serrapeptase in each capsule. Sometimes referred to as a “super enzyme,” Serrapeptase has been shown to have an effect on the movement of immune cells while the Protease blend works at normal cellular detoxification to efficiently digest all types of proteins. Pairing these enzymes with cofactor vitamins and minerals helps your body use the enzymes faster and more efficiently.
  • Easy Efficient Absorption: Formulated to be taken systemically, not digestively. It's best to take on an empty stomach, allowing enzymes to support your body rather than digest your food. Adults take 1 capsule, up to 2 times daily or as recommended by physician or healthcare professional. For best results, take on an empty stomach with a large glass of water, 30-60 minutes before or 2 hours after a meal.
  • For Most Lifestyles: MaryRuth's Serrapeptase Systemic Enzymes are Non-GMO & Vegan. Dairy Free, Nut Free, Gluten & Wheat Free, Soy Free, Nightshade Free, Sugar Free. This product CONTAINS Maltodextrin: which is corn-derived.
SaleBestseller No. 3
Vitälzym Proteolytic Systemic Enzymes Liquid Gel Capsules with Serrapeptase, Anti-inflammatory Defense Treatment, Immune and Joint Support, Natural Ache Relief Plus Fertility Supplement (360 Capsules)
  • Enteric Coated Advanced Delivery Method: Vitalzym high potency gel caps are unlike any tablet or powder based enzyme product available on the market today. Our formula contains no gluten, yeast or dairy and is designed to ensure maximum absorption into the bloodstream where it is then dispersed via your circulatory system throughout your body
  • Ingredients: Vitalzym Extra Strength premium softgels are the original, all-natural, vegetarian multi enzyme complex. Vitalzym was designed using a scientific research process to identify nature’s miracle ingredients that include Serrapeptase, Bromelain, Papain, Rutin, Amylase, Protease, Lipase and Amla Extract
  • Protect Your Health: Living well in modern times can be stressful and a source of pain at times. Vitalzym contains the most effective, purified vegan-based enzyme blend to promote healing, repair human bodily functions and leave you feeling clear and fresh
  • Small, Easy To Swallow Gel Caps: Our advanced encapsulations deliver reliable results that offer pure, potent enzymes with reliable consistency and unrivaled absorption rates. Due to the highly effective delivery rate most people need a smaller dosage, and less doses per day
  • Made In Japan: Created by a team of international scientists, Vitalzym works best when combined with exercise, proper fluid intake, and a healthy diet. It is important to be mindful of all aspects of your health. When used properly, Vitalzym can greatly increase your cardio, lung, blood flow, and immune response as well as provide joint, circulatory system and inflammation support and much more
Bestseller No. 4
Vitälzym Original Proteolytic Systemic Digestive Enzyme Formula Serrapeptase Source | Anti-Inflammatory Immune and Joint Support Increase Blood Flow Cardio Function | Healthy Men Women (450 Capsules)
  • American Made, Essential for Health, Plant Based: Not All Complete Digestive System Enzyme Products Are Made The Same - Pay For True Quality & You Will Not Be Disappointed. World Nutrition is a pioneer of complementary systemic enzymes. In 2001 we introduced the original Vitalzym pill as a hybrid formula that offers both systemic & digestive benefits to provide total body support. It quickly became the best-selling systemic enzyme in the world and sold over $10M in the first 3 years alone
  • The Best Vegetarian Digestion Supplement & Remedy: Our Premium Strength Super Gut Defense Formula contains everything you need for full-body support: Protease, Serrapeptase, Papain, Bromelain, Amylase, Lipase, Rutin, & Amla. Each powerful ingredient is derived from natural, vegetarian sources. Most competitors use enzymes harvested from pigs & cows after slaughter. These enzymes are low-quality & strength, requiring a much higher dose as they’re less effective against targeted mediators
  • Advanced, Broad Spectrum Caps Promote Wellness: Our complex extract provides the optimal potency level of proteolytic enzymes that may assist with IBS, gas, inflammation, regulating your immune system, removing excess plaque & fibrin (fibrous tissue), & support the return of blood volume & flow. Vitälzym capsules are formulated to support health in the following systems: cognitive/mental, upper respiratory, cardiovascular, gastrointestinal, reproductive, joints, connective tissue, & skin
  • Fast Response, Organic, Calms Indigestion & Assists With IBS, Gas, Bloating: Regain bowel comfort with our perfect synergistic blend of systemic and digestive enzymes. It starts in the stomach & helps the body to break down food and absorb nutrients. After helping increase digestive abilities, the systemic enzymes take action in the bloodstream, moving throughout your entire body. This unique combination can help to improve your bodily processes and regain your quality of life
  • Formulated for Active Vitality Enhancement Plus Recovery: High-quality pure powder filled capsules that break down in your stomach provide digestive support with every dose. Some serrapeptase survives the acidic environment of the stomach and a dosage is released in the small intestine, allowing it to be absorbed into your bloodstream and distributed throughout your whole body. Our customers have reported increased energy, stamina, and recovery from intense exercise
Bestseller No. 5
AST Enzymes Excellacor – Proteolytic Systemic Enzymes Formula – with Enteric-Coated Serrapeptase - Total Body Support - 90 Vegetarian Capsules
  • ADVANCED SYSTEMIC ENZYME FORMULA: a potent blend of enteric-coated Serrapeptase, proteases and herbs that synergistically support the body’s natural response to inflammation and joint function; used for more than a decade by thousands of people as a daily dietary supplement.*
  • RANGE OF USE: Supports the body’s natural response to inflammation including fatigued muscles and joint function, healthy blood circulation, and healthy fibrin metabolism.*
  • ACHIEVE OPTIMAL HEALTH: Elimination of potential waste substances from the body is a crucial step in metabolic processes for optimal health. Excellacor improves the body’s ability to rid of these wastes and restore normal balance.*
  • QUALITY ASSURED: All products by AST Enzymes are manufactured in the USA, free of animal derivatives, dairy, yeast, fish or shellfish, peanuts, and tree nuts.
Bestseller No. 6
Doctor's Best Proteolytic enzymes, Digestion, Muscle, Joint, Non-GMO, Gluten Free, Vegetarian, 90 Veggie Caps
  • Doctor's Best Proteolytic Enzymes is a potent formulation containing a broad spectrum of proteolytic enzymes (proteases).
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
  • Proteolytic enzymes function in the body to digest and break down proteins into their amino acid components
  • Proteolytic Enzymes Provide Support for Muscle, Joint, and Overall Tissue Health
  • Proteolytic Enzymes will appear in clear encapsulation, with no enteric coating and the potency, safety and quality of this product will remain the same
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Bestseller No. 7
HCP Formulas - Fibrenza - Systemic Enzyme Complex with Fibrinolytic & Proteolytic Enzymes - Fibrin Defense, Inflammation & Cardiovascular Support - Vegetarian - Dietary Supplement - 60 Caps
  • FIBRENZA SUPPLEMENT: An advanced blend of 13 powerful systemic enzymes! HCP Formulas' Fibrenza is a natural systemic enzyme complex. Formulated with fibrinolytic & proteolytic enzymes, Fibrenza supports the body's ability to dissolve fibrin, maintain a healthy inflammatory response and cleanse the body of impurities for maximum body-wide benefits in a reliable, time-released capsule.
  • INFLAMMATION & CARDIOVASCULAR SUPPORT: Aging lowers your body's ability to produce sufficient levels of enzymes, often leading to inflammation and build-up of fibrin. Fibrenza harnesses potent systemic enzymes that break down proteins, toxins, and other cellular debris, such as Serrapeptase and Nattokinase—promoting powerful fibrin and anti-inflammatory defense essential for a healthy cardiovascular system.
  • ANTIOXIDANT: Not only are systemic enzymes powerful anti-inflammatory and anti-fibrin agents, but they also possess profound antioxidant properties. The foundation of anti-aging and detoxification protocols, Superoxide Dismutase helps break down potentially harmful oxygen molecules in cells that can cause tissue damage for better overall well-being.
  • SUPERIOR DELIVERY: Fibrenza utilizes a technologically advanced capsule without phthalates or chemicals. Unlike enteric coatings, AcidDefenz capsules use a non-GMO vegetable cellulose barrier to provide maximum protection against harsh stomach acids. They are time-released for more consistent enzyme absorption into the bloodstream every time.
  • PREMIUM INGREDIENTS: HCP Formulas specializes in ultra-premium nutraceutical supplements to better support your health. We source only the highest-grade Non-GMO ingredients that are vegetarian and free of gluten, dairy, wheat, yeast, and shellfish. Fibrenza contains NO Magnesium Stearate, Phthalates, Talc, or artificial colors or flavors and is proudly manufactured in the USA in GMP registered facilities.
Bestseller No. 8
Serracor-NK –Proteolytic Systemic Enzyme Formula – Contains Enteric-Coated Serrapeptase and Enteric-Coated Nattokinase - Circulatory and Respiratory Support – 90 Vegetarian Capsules–AST Enzymes
  • ADVANCED SYSTEMIC ENZYME FORMULA: Serracor-NK is a powerful blend of enteric-coated Serrapeptase and Nattokinase, systemic enzymes studied for their fibrinolytic properties, with antioxidant herbs, CoEnzyme Q10 and magnesium. Serracor-NK supports a healthy circulatory system and normal fibrin metabolism.*
  • RANGE OF USE: Supports the body’s natural response to inflammation including respiratory and sinus, and cardiovascular health.*
  • ACHIEVE OPTIMUM HEALTH: Excess fibrin in the body can do more harm than good. A high level of circulating fibrin has the potential to accelerate scarring, increase clot formation and impede normal blood flow. This can cause issues leading to cardiovascular dysfunction. The combination of Serrapeptase and nattokinase used in addition to a complete array of proteolytic enzymes, makes Serracor-NK a unique blend designed to support maximum circulatory health.*
  • QUALITY ASSURED: All products by AST Enzymes are manufactured in the USA. Free of animal derivatives, dairy, yeast, fish or shellfish, peanuts, and tree nuts.
Bestseller No. 9
HCP Formulas - Fibrenza - Systemic Enzyme Complex with Fibrinolytic & Proteolytic Enzymes - Fibrin Defense & Cardiovascular Support - Vegetarian - Dietary Supplement - 240 Caps
  • FIBRENZA SUPPLEMENT: An advanced blend of 13 powerful systemic enzymes! HCP Formulas' Fibrenza is a natural systemic enzyme complex. Formulated with fibrinolytic & proteolytic enzymes, Fibrenza supports the body's ability to dissolve fibrin, and cleanse the body of impurities for maximum body-wide benefits in a reliable, time-released capsule.
  • INFLAMMATION & CARDIOVASCULAR SUPPORT: Aging lowers your body's ability to produce sufficient levels of enzymes, often leading to inflammation and build-up of fibrin. Fibrenza harnesses potent systemic enzymes that break down proteins, toxins, and other cellular debris, such as Serrapeptase and Nattokinase—promoting powerful fibrin and anti-inflammatory defense essential for a healthy cardiovascular system.
  • ANTIOXIDANT: Not only are systemic enzymes powerful anti-inflammatory and anti-fibrin agents, but they also possess profound antioxidant properties. The foundation of anti-aging and detoxification protocols, Superoxide Dismutase helps break down potentially harmful oxygen molecules in cells that can cause tissue damage for better overall well-being.
  • SUPERIOR DELIVERY: Fibrenza utilizes a technologically advanced capsule without phthalates or chemicals. Unlike enteric coatings, AcidDefenz capsules use a non-GMO vegetable cellulose barrier to provide maximum protection against harsh stomach acids. They are time-released for more consistent enzyme absorption into the bloodstream every time.
  • PREMIUM INGREDIENTS: HCP Formulas specializes in ultra-premium nutraceutical supplements to better support your health. We source only the highest-grade Non-GMO ingredients that are vegetarian and free of gluten, dairy, wheat, yeast, and shellfish. Fibrenza contains NO Magnesium Stearate, Phthalates, Talc, or artificial colors or flavors and is proudly manufactured in the USA in GMP registered facilities.

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